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Steven F Maier Selected Research

Hyperalgesia

1/2022Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists.
1/2021Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain.
1/2019A single peri-sciatic nerve administration of the adenosine 2A receptor agonist ATL313 produces long-lasting anti-allodynia and anti-inflammatory effects in male rats.
1/2018MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats.
1/2018Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.
1/2018DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats.
1/2018Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A2A receptor agonists.
8/2017Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia.
1/2017Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury.
1/2017Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators.
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Steven F Maier Research Topics

Disease

56Pain (Aches)
10/2021 - 01/2003
54Hyperalgesia
01/2022 - 12/2001
35Neuralgia (Stump Neuralgia)
10/2022 - 02/2003
18Shock
01/2021 - 01/2002
17Infections
05/2018 - 02/2005
16Inflammation (Inflammations)
01/2021 - 01/2004
11Neuroinflammatory Diseases
10/2021 - 10/2011
6Chronic Pain
11/2019 - 03/2005
4Peripheral Nerve Injuries
01/2022 - 11/2008
4Memory Disorders (Memory Loss)
01/2021 - 10/2004
4Wounds and Injuries (Trauma)
01/2017 - 11/2012
4Fever (Fevers)
10/2011 - 02/2003
4Bacterial Infections (Bacterial Infection)
08/2011 - 04/2008
4Opioid-Related Disorders (Opiate Addiction)
01/2010 - 02/2007
3Contusions
01/2019 - 01/2017
3Migraine Disorders (Migraine)
01/2017 - 01/2012
3Escherichia coli Infections
01/2015 - 02/2010
3AIDS-Related Complex (ARC)
08/2012 - 01/2010
3Respiratory Insufficiency (Respiratory Failure)
01/2010 - 11/2008
2Postoperative Cognitive Complications
01/2021 - 10/2012
2Brain Diseases (Brain Disorder)
01/2021 - 05/2015
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2021 - 01/2017
2Hypersensitivity (Allergy)
11/2019 - 03/2015
2Obesity
10/2017 - 11/2014
2Mood Disorders (Mood Disorder)
01/2017 - 11/2003
2Substance-Related Disorders (Drug Abuse)
01/2015 - 06/2011
2Peripheral Nervous System Diseases (PNS Diseases)
11/2012 - 07/2007
2Cognitive Dysfunction
06/2012 - 08/2011

Drug/Important Bio-Agent (IBA)

49CytokinesIBA
01/2022 - 01/2003
22Morphine (MS Contin)FDA LinkGeneric
01/2022 - 01/2002
18Opioid Analgesics (Opioids)IBA
01/2021 - 12/2005
14Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2005
14Toll-Like Receptor 4IBA
01/2021 - 07/2008
13Interleukin-1 (Interleukin 1)IBA
08/2017 - 02/2003
11Interleukin-10 (Interleukin 10)IBA
01/2019 - 03/2004
9Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2021 - 03/2004
9Brain-Derived Neurotrophic Factor (BDNF)IBA
05/2018 - 10/2004
8Messenger RNA (mRNA)IBA
01/2021 - 10/2004
8Interleukin-6 (Interleukin 6)IBA
01/2021 - 02/2003
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019 - 02/2003
8LipopolysaccharidesIBA
02/2015 - 08/2005
8Interleukin-1beta (Interleukin 1 beta)IBA
11/2014 - 11/2003
8Pharmaceutical PreparationsIBA
09/2011 - 12/2003
7Serotonin (5 Hydroxytryptamine)IBA
01/2017 - 02/2002
7Analgesics (Analgesic Drugs)IBA
09/2011 - 08/2004
6Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
11/2012 - 08/2004
5Toll-Like Receptors (Toll-Like Receptor)IBA
01/2021 - 11/2007
5Adenosine (Adenocard)FDA LinkGeneric
01/2019 - 11/2009
5InflammasomesIBA
01/2018 - 08/2015
5HMGB1 Protein (HMG1)IBA
01/2018 - 12/2003
5Minocycline (Cyclops)FDA LinkGeneric
01/2017 - 05/2005
5ChemokinesIBA
01/2017 - 08/2004
5CorticosteroneIBA
10/2011 - 02/2003
4Naltrexone (ReVia)FDA LinkGeneric
01/2021 - 07/2008
4ATL 313IBA
01/2019 - 11/2009
4salicylhydroxamic acid (SHAM)IBA
01/2019 - 11/2009
4GlucocorticoidsIBA
11/2018 - 06/2011
4Dinoprostone (PGE2)FDA Link
01/2017 - 01/2010
3Neutralizing AntibodiesIBA
01/2019 - 03/2004
3Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2019 - 03/2004
3BradykininIBA
01/2017 - 01/2010
3Histamine (Histamine Dihydrochloride)FDA Link
01/2017 - 01/2010
3ibudilastIBA
01/2017 - 02/2009
3Ethanol (Ethyl Alcohol)IBA
08/2015 - 05/2013
3Freund's AdjuvantIBA
02/2014 - 01/2012
3Formaldehyde (Formol)FDA Link
02/2014 - 10/2010
3Naloxone (Narcan)FDA LinkGeneric
05/2012 - 07/2008
3Glycoproteins (Glycoprotein)IBA
01/2010 - 10/2005
2Superoxides (Superoxide)IBA
10/2022 - 12/2016
2Pathogen-Associated Molecular Pattern MoleculesIBA
01/2022 - 01/2017
2MicroRNAs (MicroRNA)IBA
10/2021 - 01/2018
2Interleukin-17 (Interleukin 17)IBA
01/2021 - 01/2021
2Opioid Receptors (Opioid Receptor)IBA
01/2021 - 11/2009
2Toll-Like Receptor 2IBA
01/2021 - 05/2012
2NLR ProteinsIBA
01/2019 - 01/2016
2NF-kappa B (NF-kB)IBA
01/2019 - 10/2005
2Dopamine (Intropin)FDA LinkGeneric
01/2019 - 11/2007
2LigandsIBA
01/2018 - 01/2017
22- (4- (2- carboxyethyl)phenethylamino)- 5'- N- ethylcarboxamidoadenosineIBA
01/2018 - 11/2009
2Neurotransmitter Agents (Neurotransmitter)IBA
12/2016 - 03/2007
2GlucuronidesIBA
02/2015 - 05/2013
2morphine-3-glucuronideIBA
02/2015 - 05/2013
2ethyl glucuronideIBA
02/2015 - 05/2013
2alpha7 Nicotinic Acetylcholine ReceptorIBA
12/2012 - 08/2010
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
12/2012 - 08/2010
2Narcotic Antagonists (Opioid Antagonists)IBA
05/2012 - 07/2008
2Glutamic Acid (Glutamate)FDA Link
09/2011 - 07/2004
2AntibodiesIBA
08/2010 - 11/2009
2DNA (Deoxyribonucleic Acid)IBA
07/2007 - 12/2006

Therapy/Procedure

16Therapeutics
01/2022 - 07/2004
11Analgesia
12/2016 - 08/2004
10Spinal Injections
01/2018 - 03/2005
4Laparotomy
01/2019 - 10/2010
3Subcutaneous Injections
01/2012 - 03/2004
3Injections
01/2012 - 12/2003
2Behavior Control
06/2019 - 09/2012
2Catheters
01/2017 - 01/2012
2Pain Management
01/2016 - 04/2015
2Ligation
10/2013 - 05/2012
2Operative Surgical Procedures
01/2012 - 01/2004